Breast cancer
 
Breast cancer

rs2279744
 Genotype  Effect
   TT    normal
   GT    generally more cancer prone
   GG    generally more cancer prone
Cell. 2004 Nov 24;119(5):591-602. 
J Med Genet. 2006 Jun;43(6):531-3. 
J Natl Cancer Inst. 2006 Jul 5;98(13):911-9. 
Int J Cancer. 2008 Feb 15;122(4):915-8. 
Eur J Cancer. 2008 Mar;44(5):760-6. 
Carcinogenesis. 2007 Nov;28(11):2262-7. 
Gynecol Oncol. 2007 Mar;104(3):660-4. 
Cancer. 2008 Aug 15;113(4):799-807. 
BMC Cancer. 2008 Oct 1;8:281. 
Cancer Causes Control. 2008 Sep 24. [Epub ahead of print]   
 
rs4680
 Genotype  Effect
   AA    multiple associations, see details
   AG    multiple associations, see details
   GG    multiple associations, see details
Thromb Haemost. 2007 Dec;98(6):1226-31. 
Biol Psychiatry. 2005 May 15;57(10):1117-27. 
BMC Cancer. 2008 Jan 14;8:6. 
Neuropsychopharmacology. 2008 Dec;33(13):3078-84. 
Psychopharmacology (Berl). 2008 Nov 7. [Epub ahead of print]   

 
rs2056116
 Genotype  Effect
   AA    normal risk
   AG    1.18x risk for breast cancer
   GG    1.41x risk for breast cancer
Carcinogenesis. 2008 Feb;29(2):351-5. 
 
rs438034
 Genotype  Effect
   CC    normal
   CT    poorer survival rate if breast cancer patient
   TT    poorer survival rate if breast cancer patient
Eur J Cancer. 2008 Nov 11. [Epub ahead of print] 
 
rs11045585
 Genotype  Effect
   AA    24% chance (lower than average) of docetaxel-induced leukopenia/neutropenia
   AG    63% chance (higher than average) of docetaxel-induced leukopenia/neutropenia
   GG    (no data; implied high chance of docetaxel-induced leukopenia/neutropenia)
Cancer Sci. 2008 May;99(5):967-72. 
 
rs2273535
 Genotype  Effect
   AA    common
   AT    higher cancer risk
   TT    higher cancer risk
Carcinogenesis. 2005 Aug;26(8):1368-73. 
Carcinogenesis. 2004 Nov;25(11):2225-30. 
Carcinogenesis. 2007 Feb;28(2):350-5. 
Int J Cancer. 2008 Jul 15;123(2):380-8.   
 
rs4076128
 Genotype  Effect
   AA    1.8x increased breast cancer risk for women having high linoleic acid diets
   AG    normal
   GG    normal
Cancer Epidemiol Biomarkers Prev. 2008 Oct;17(10):2748-54. 
 
rs2910164
 Genotype  Effect
   CC    higher/earlier cancer likelihood??
   CG    higher/earlier cancer likelihood??
   GG    normal
Proc Natl Acad Sci U S A. 2008 May 20;105(20):7269-74. 
Carcinogenesis. 2008 Oct;29(10):1963-6. 
Carcinogenesis. 2008 Nov;29(11):2126-31.   
 
rs2981579
 Genotype  Effect
   CC    common
   CT    1.20x risk for breast cancer
   TT    1.64x risk for breast cancer
Nat Genet. 2007 Jul;39(7):870-4. 
 
rs2981582
 Genotype  Effect
   CC    normal
   CT    1.3x higher risk of ER+ breast cancer
   TT    1.7x higher risk of ER+ breast cancer
Nature. 2007 Jun 28;447(7148):1087-93. 
PLoS Genet. 2008 Apr 25;4(4):e1000054. 
N Engl J Med. 2008 Jun 26;358(26):2796-803. 
Carcinogenesis. 2008 Oct 8. [Epub ahead of print] 
Int J Cancer. 2009 Feb 1;124(3):729-33. 
Breast Cancer Res Treat. 2008 Nov 13. [Epub ahead of print] 
Carcinogenesis. 2008 Nov 20. [Epub ahead of print] 
 
rs144848
 Genotype  Effect
   TT    normal
   GT    possible increased risk for breast cancer
   GG    1.3x increased risk for breast cancer
Hum Mol Genet. 2007 May 1;16(9):1051-7. 
Nat Genet. 2000 Nov;26(3):362-4. 
 
rs3738579
 Genotype  Effect
   CC    1.5x increased risk for breast cancer, HNSCC
   CT    0.5x decreased risk for several cancers
   TT    1.3x - 2x increased risk for several cancers
PLoS ONE. 2008 Jun 25;3(6):e2492. 
 
rs1978503
 Genotype  Effect
BMC Med Genet. 2007 Sep 19;8 Suppl 1:S6. 
 
rs1926657
 Genotype  Effect
BMC Med Genet. 2007 Sep 19;8 Suppl 1:S6. 
 
rs10515860
 Genotype  Effect
   AA    ?
   AG    ?
   GG    ?
rs6556756
 Genotype  Effect
BMC Med Genet. 2007 Sep 19;8 Suppl 1:S6. 
 
rs12951053
 Genotype  Effect
   AA    ?
   AC    ?
   CC    ?
Int J Cancer. 2007 Dec 1;121(11):2532-8. 
 
rs1801270
 Genotype  Effect
   AA    normal risk
   AC    increased risk for lung cancer
   CC    increased risk for lung cancer
Hum Hered. 1996 Jul-Aug;46(4):221-5. 
 
rs2854344
 Genotype  Effect
   AA    normal risk
   AG   
   GG    1.25x risk of developing ovarian cancer
Br J Cancer. 2006 Jun 19;94(12):1921-6. 
Cancer Res. 2006 Oct 15;66(20):10220-6. 
Int J Cancer. 2008 Jul 15;123(2):380-8. 
 
rs1008805
 Genotype  Effect
   CC    ?
   CT    ?
   TT    ?
rs2241766
 Genotype  Effect
   TT    normal
   GT    0.6x decreased risk for breast cancer
   GG    normal
Cancer Res. 2008 May 1;68(9):3178-84. 
 
rs3176336
 Genotype  Effect
   AA    normal risk
   AT    ?
   TT    1.25x higher risk for breast cancer
Carcinogenesis. 2008 Feb;29(2):333-41. 
 
rs1042522
 Genotype  Effect
   CC    longer lifespan?
   CG    ?
   GG    ?
Hum Mol Genet. 2007 May 1;16(9):1051-7. 
Cell Cycle. 2008 Jan 15;7(2):158-63. 
Cancer. 2008 Aug 15;113(4):799-807. 
Diabetes. 2008 Nov;57(11):3136-44. 
 
rs12762549
 Genotype  Effect
   CC    ?
   CG    ?
   GG    ?
Cancer Sci. 2008 May;99(5):967-72. 
 
rs4987945
 Genotype  Effect
   CC    ?
   CG    ?
   GG    ?
Hum Mol Genet. 2007 May 1;16(9):1051-7. 
 
rs2479717
 Genotype  Effect
   AA    ?
   AT    ?
   TT    ?
Breast Cancer Res. 2008;10(3):R47. 
 
rs1061646
 Genotype  Effect
   CC    1.16x increased risk for breast cancer
   CT    1.08x increased risk for breast cancer
   TT    normal risk
Hum Mol Genet. 2008 Mar 15;17(6):825-34. 
 
rs1219648
 Genotype  Effect
   AA    common
   AG    1.20x risk for breast cancer
   GG    1.64x risk for breast cancer
Nat Genet. 2007 Jul;39(7):870-4. 
Hum Reprod. 2008 Jul;23(7):1661-8. 
Cancer Epidemiol Biomarkers Prev. 2008 May;17(5):1060-5. 
Carcinogenesis. 2008 Oct 8. [Epub ahead of print] 
Int J Cancer. 2009 Feb 1;124(3):729-33. 
Carcinogenesis. 2008 Nov 20. [Epub ahead of print] 
 
rs3803662
 Genotype  Effect
   CC    normal
   CT    ?
   TT    1.6x increased risk for breast cancer
Nature. 2007 Jun 28;447(7148):1087-93. 
Nat Genet. 2007 Jul;39(7):865-9. 
Breast Cancer Res. 2007;9(6):R78. 
PLoS Genet. 2008 Apr 25;4(4):e1000054. 
Breast Cancer Res Treat. 2008 Nov 13. [Epub ahead of print] 
 
rs12255372
 Genotype  Effect
   TT    increased breast cancer and aggressive prostate cancer risk
   GT    ?
   GG    normal breast cancer risk
BMC Cancer. 2006 Nov 17;6:268. 
Diabetes. 2006 Sep;55(9):2649-53. 
J Clin Invest. 2007 Aug;117(8):2155-63. 
J Clin Endocrinol Metab. 2008 Jan;93(1):304-9. 
Prostate. 2008 May 15;68(7):740-7. 
Diabetes. 2008 Nov 25. [Epub ahead of print]