Crohn's disease
 
Crohn's disease

   
 
rs2201841
 Genotype  Effect
   CC    1.5x risk for Crohn's disease
   CT    1.5x risk for Crohn's disease; 2x risk for Graves' disease
   TT    2.4x risk for Graves' disease
Science. 2006 Dec 1;314(5804):1461-3. 
J Clin Endocrinol Metab. 2008 Mar;93(3):1077-81. 
Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14747-52. 
 
rs12037606  
 Genotype  Effect
   AA    1.5x risk
   AG    1.2x risk
   GG    normal
Nature. 2007 Jun 7;447(7145):661-78. 
 
rs6601764  
 Genotype  Effect
   CC    1.5x risk
   CT    1.1x risk
   TT    normal
Nature. 2007 Jun 7;447(7145):661-78. 
 
rs10761659
 Genotype  Effect
   AA    normal
   AG    1.2x risk
   GG    1.5x risk
Nature. 2007 Jun 7;447(7145):661-78. 
 
rs1793004
 Genotype  Effect
   CC    increased risk for Crohn's disease
   CG    ?
   GG    0.89x decreased risk for Crohn's disease
PLoS ONE. 2007 Aug 8;2(1):e691. 
 
rs11362  
 Genotype  Effect
   AA    normal risk
   AG    2.4x increased risk for one form of Crohn's disease
   GG    normal risk
Scand J Gastroenterol. 2007 Oct 18:1-9. [Epub ahead of print] 
Scand J Gastroenterol. 2008 Mar;43(3):299-307. 
 
rs10883365  
 Genotype  Effect
   AA    normal
   AG    1.2x increased risk for Crohn's disease
   GG    1.6x increased risk for Crohn's disease
Nature. 2007 Jun 7;447(7145):661-78. 
Gut. 2008 Nov 6. [Epub ahead of print] 
Nat Genet. 2007 Jul;39(7):830-2. 
 
rs9469220  
 Genotype  Effect
   AA    1.5x risk
   AG    1.1x risk
   GG    normal
Nature. 2007 Jun 7;447(7145):661-78. 
 
rs7753394
 Genotype  Effect
   CC    1.5x risk
   CT    1.2x risk
   TT    normal
Nature. 2007 Jun 7;447(7145):661-78. 
 
rs6908425
 Genotype  Effect
   CC    1.9x risk
   CT    1.6x risk
   TT    normal
Nature. 2007 Jun 7;447(7145):661-78. 
 
rs1800795  
 Genotype  Effect
   CC    less IL6; certain risks, see details
   CG    complex; see details
   GG    more IL6; certain risks, see details
J Clin Invest. 1998 Oct 1;102(7):1369-76. 
J Clin Endocrinol Metab. 2004 Oct;89(10):5053-8. 
J Am Soc Nephrol. 2006 Aug;17(8):2333-40. 
Transplantation. 2002 Nov 15;74(9):1297-302. 
Blood. 2000 Oct 1;96(7):2562-7. 
Ann Oncol. 2007 Aug;18(8):1376-81. 
Int J Cardiol. 2005 Sep 1;103(3):266-71. 
Thromb Res. 2003 Jun 1;110(4):181-6. 
Am J Hypertens. 2005 Apr;18(4 Pt 1):517-22. 
Arch Med Res. 2007 Jul;38(5):551-5. 
Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13260-5. 
Biochim Biophys Acta. 2005 May 15;1734(2):143-51. 
Hum Immunol. 2006 Oct;67(10):819-25. 
J Soc Gynecol Investig. 2003 Jan;10(1):32-6. 
J Clin Endocrinol Metab. 2002 Mar;87(3):1134-41. 
Pediatrics. 2007 Oct;120(4):814-23. 
Diabetes. 2008 Jan;57(1):244-54. 
Metabolism. 2007 Dec;56(12):1643-8. 
Mol Genet Metab. 2004 Jun;82(2):180-6. 
Diabetes Res Clin Pract. 2006 Mar;71(3):299-305. 
Kidney Int. 2003 Aug;64(2):616-22. 
Kidney Int. 2002 Nov;62(5):1824-7. 
J Urol. 2005 Aug;174(2):753-6. 
Arterioscler Thromb Vasc Biol. 2002 Dec 1;22(12):2066-71. 
Stroke. 2005 Sep;36(9):1854-8. 
Heart Surg Forum. 2005;8(3):E140-5; discussion E145. 
J Periodontol. 2006 Dec;77(12):1978-83. 
Clin Exp Immunol. 2007 Apr;148(1):119-26. 
Neurobiol Aging. 2003 Nov;24(7):921-6. 
Mech Ageing Dev. 2005 Mar;126(3):417-8. 
Arthritis Res Ther. 2008;10(1):R21. 
Ann N Y Acad Sci. 2007 Nov;1119:196-202. 
Thromb Haemost. 2008 May;99(5):944-50. 
 
rs7807268
 Genotype  Effect
   CC    normal
   CG    1.3x risk
   GG    1.4x risk
Nature. 2007 Jun 7;447(7145):661-78. 
 
rs17221417
 Genotype  Effect
   CC    normal
   CG    1.3x risk
   GG    1.9x risk
Nature. 2007 Jun 7;447(7145):661-78. 
 
rs7746082
 Genotype  Effect
Nat Genet. 2008 Aug;40(8):955-62. 
 
rs6596075
 Genotype  Effect
   CC    2x risk
   CG    1.5x risk
   GG    normal
Nature. 2007 Jun 7;447(7145):661-78. 
 
rs1800972
 Genotype  Effect
   CC    normal risk
   CG    normal risk
   GG    reduced risk for Crohn's disease
Scand J Gastroenterol. 2007 Oct 18:1-9. [Epub ahead of print] 
Scand J Gastroenterol. 2008 Mar;43(3):299-307. 
 
rs10210302
 Genotype  Effect
   CC    normal
   CT    1.2x risk
   TT    1.8x risk
Nature. 2007 Jun 7;447(7145):661-78. 
 
rs2076756
 Genotype  Effect
   AA    normal
   AG    ?
   GG    1.7x increased risk for Crohn's disease
PLoS ONE. 2007 Aug 8;2(1):e691.    
 
rs11209026
 Genotype  Effect
   AA    0.26x lower risk for certain autoimmune diseases
   AG    0.26x lower risk for certain autoimmune diseases
   GG    common
Science. 2006 Dec 1;314(5804):1461-3. 
Am J Gastroenterol. 2008 Mar;103(3):621-7. 
Nat Genet. 2007 Nov;39(11):1329-37. 
J Invest Dermatol. 2008 Jul;128(7):1653-61. 
Am J Gastroenterol. 2008 Mar;103(3):615-20. 
World J Gastroenterol. 2008 Aug 7;14(29):4643-51. 
 
rs1000113
 Genotype  Effect
   CC    normal
   CT    1.5x risk of Crohn's disease
   TT    1.9x risk of Crohn's disease
Nature. 2007 Jun 7;447(7145):661-78.