Alcoholism
 
Alcoholism

rs1800497
 Genotype  Effect
   CC    A2/A2 bupropion effective
   CT    A1/A2 bupropion ineffective
   TT    A1/A1 bupropion ineffective, diminished pleasure response
Mol Psychiatry. 1998 May;3(3):256-60. 
Pharmacogenetics. 1996 Aug;6(4):297-305. 
Nicotine Tob Res. 2004 Aug;6(4):583-97. 
Nicotine Tob Res. 2007 Dec;9(12):1251-7. 
Brain Inj. 2008 Aug;22(9):705-14. 
 
rs1229984
 Genotype  Effect
   AA    0.56x decreased risk of oral/throat cancers
   AG    0.56x decreased risk of oral/throat cancers
   GG    normal; more frequent alcohol consumption
Hum Genet. 1995 Aug;96(2):151-4. 
Nat Genet. 2008 Jun;40(6):707-9. 
Hum Mol Genet. 2008 Nov 7. [Epub ahead of print] 
 
rs1042173
 Genotype  Effect
   TT    among alcoholics, likely to be heavier drinkers
   GT    normal
   GG    normal
Alcohol Clin Exp Res. 2008 Nov 19. [Epub ahead of print] 
 
rs1076560
 Genotype  Effect
   AA    ?
   AC    ?
   CC    ?
Neurosci Lett. 2007 Jan 29;412(2):139-42. 
 
rs279858
 Genotype  Effect
   AA    ?
   AG    ?
   GG    apparently more prone to alcoholism
Neuropsychopharmacology. 2005 Jun;30(6):1193-203. 
Am J Hum Genet. 2004 Apr;74(4):705-14. 
Addiction. 2008 Jun;103(6):1027-38. 
 
rs279845
 Genotype  Effect
   AA    ?
   AT    ?
   TT    ?
Am J Hum Genet. 2004 Apr;74(4):705-14. 
 
rs2066702
 Genotype  Effect
   CC    alcoholism risk for African-Americans
   CT    ?
   TT    ?
rs279871
 Genotype  Effect
   AA    ?
   AG    ?
   GG    ?
Am J Hum Genet. 2004 Apr;74(4):705-14. 
 
rs27072
 Genotype  Effect
   CC    2x risk of severe alcohol withdrawal
   CT    normal
   TT    normal
Alcohol Clin Exp Res. 2008 Jan;32(1):27-35. 
 
rs27048
 Genotype  Effect
   CC    2x risk of severe alcohol withdrawal
   CT    normal
   TT    normal
Alcohol Clin Exp Res. 2008 Jan;32(1):27-35.